BIO-IMAGING

As part of our efforts to apply materials science characterization to study relevant biomedical systems, we have been developing new methods for the application of Focused Ion Beam/ Ion Microscopy/Electron Microscopy to the study of biomedical samples. So far we have created a novel microscopy technique (Correlative Light-Ion Microscopy (CLIM)), and are in the process of developing other new methods using the unique potentialities provided by FIB for TEM sample preparation and 3D reconstruction of a micro region.

PUBLICATIONS

 

 

 

2018

  • von Erlach, T. C., Bertazzo, S., Wozniak, M. A., Horejs, C. M., Maynard, S. A., Attwood, S., . . . Stevens, M. M. (2018). Cell-geometry-dependent changes in plasma membrane order direct stem cell signalling and fate. Nature Materials, 1-6.

 

 

  • Fuhrmann, G., Chandrawati, R., Parmar, P. A., Keane, T. J., Maynard, S. A., Bertazzo, S., & Stevens, M. M. (2018). Engineering Extracellular Vesicles with the Tools of Enzyme Prodrug Therapy. Advanced materials (Deerfield Beach, Fla.).

 

  • Keevend, K., Panzarasa, G., Starsich, F. H. L., Zeltner, M., Spyrogianni, A., Tsolaki, E., . . . Herrmann, I. K. (2018). Facile meltPEGylation of flame-made luminescent Tb3+-doped yttrium oxide particles: hemocompatibility, cellular uptake and comparison to silica. Chemical Communications, 54 (23), 2914-2917. doi:10.1039/c7cc09402g

 

  • Millership, S. J., Xavier, G. D. S., Choudhury, A. I., Bertazzo, S., Chabosseau, P., Pedroni, S. M. A., . . . Withers, D. J. (2018). Neuronatin regulates pancreatic beta cell insulin content and secretion. Journal of Clinical Investigation, 128 (8), 3369-3381. doi:10.1172/JCI120115

 

  • Ryabova, A. V., Keevend, K., Tsolaki, E., Bertazzo, S., Pominova, D. V., Romanishkin, I. D., . . . Orlovskii, Y. V. (2018). Visualization of Nd3+-doped LaF3nanoparticles for near infrared bioimaging via upconversion luminescence at multiphoton excitation microscopy. Biomedical Photonics, 7 (1), 4-12.

 

2017

  • Clarke, D. E., Pashuck, E. T., Bertazzo, S., et al (2017). Self-Healing, Self-Assembled β-Sheet Peptide-Poly(γ-glutamic acid) Hybrid Hydrogels. Journal of the American Chemical Society, 139 (21), 7250-7255.

 

  • Matter, M. T., Starsich, F., Galli, M., Hilber, M., Schlegel, A. A., Bertazzo, S., . . . Herrmann, I. K. (2017). Developing a tissue glue by engineering the adhesive and hemostatic properties of metal oxide nanoparticles. Nanoscale, 9 (24), 8418-8426. doi:10.1039/c7nr01176h

  • Bohmer, N., Demarmels, N., Tsolaki, E., Gerken, L., Keevend, K., Bertazzo, S., . . . Herrmann, I. K. (2017). Removal of Cells from Body Fluids by Magnetic Separation in Batch and Continuous Mode: Influence of Bead Size, Concentration, and Contact Time. ACS APPLIED MATERIALS & INTERFACES, 9 (35), 29571-29579. doi:10.1021/acsami.7b10140

 

 

  • Keevend, K., Stiefel, M., Neuer, A. L., Matter, M. T., Neels, A., Bertazzo, S., & Herrmann, I. K. (2017). Tb3+-doped LaF3 nanocrystals for correlative  cathodoluminescence electron microscopy imaging with nanometric resolution in  focused ion beam-sectioned biological samples. Nanoscale, 9 (13), 4383-4387.

- Selected for inside cover

 

2016

 

  • Lattuada, M., Ren, Q., Zuber, F., Galli, M., Bohmer, N., Matter, M. T., . . .  Herrmann, I. K. (2016). Theranostic body fluid cleansing: rationally designed magnetic particles enable capturing and detection of bacterial pathogens. Journal of Materials Chemistry B, 4 (44), 7080-7086.

- Selected for Back cover

 

  • Belu, A., Schnitker, J., Bertazzo, S., Neumann, E., Mayer, D., Offenhaeusser, A., &

Santoro, F. (2016). Ultra-thin resin embedding method for scanning electron microscopy of individual cells on high and low aspect ratio 3D nanostructures. Journal of Microscopy, 263 (1), 78-86.

 

2015

 

 

2014

 

 

 

 

2012

- Featured in Nature

- Featured in Chemistry World

- technological MarblarSelected by Royal Society of Chemistry for sponsoring in webpage